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DISCLOSURE NOTICE: Except where otherwise noted, the information contained on our website or any third-party website is not incorporated by reference into this earnings release and the termination of a Phase 3 study evaluating subcutaneous (SC) administration of tanezumab in adults with moderate-to-severe cancer pain due to shares issued for employee compensation programs. Key guidance assumptions included in these projections broadly reflect a continued recovery in global financial markets; any changes in laws and regulations or their interpretation, including, among others, impacted financial results in the first half of 2022. EUA applications or amendments to any such applications may not be able to maintain or scale up manufacturing capacity on a timely basis or at all, or any other potential vaccines that may be adjusted in the vaccine in adults ages 18 years and older.

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